Say, for some reason, you just got yourself a brand new Kindle Fire and for some reason don't want to run the custom launcher Amazon's whipped up. (And it's pretty darn good, actually.) Now that we've got proper ADB access, loading a third-party launcher is just a few clicks away. (Or you can install through a file explorer on the device, if you want.)
We've got ADW.EX running with nary a problem. And just like on any other smartphone or tablet, you can set it to be the default launcher. You've still got Amazon's menu bars on the top and bottom, but...
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Kindle Fire runs third-party launchers just fine, thank you very much